Welcome to the Ophthalmology Journal News page! This page will showcase the latest news from the world of Ophthalmology, as published by The British Journal of Ophthalmology (BMJ).
For the British Ophthalmology Journal Archives, please visit http://bjo.bmj.com/ .
These news items are mainly specific study results that are relevant to the layman.
We have also added another news page with more ‘general’ Opthalmogy news here: Opthamologist News.
Furthermore, we have added a page with general news articles about Eye Health here: Eye Problems Articles , which is a good read for both patients and Ophthalmologists alike.
Ophthalmology Journal News:
We read with interest the recent article by Flores-Moreno et al
In this study, foveal thickness was measured from the hyper-reflective line corresponding...
Basal cell carcinoma (BCC) is the most common cancer worldwide, and 85% of all BCCs occur in the head and neck. In the periocular region, recurrent BCC is associated with significant morbidity and, therefore, the ability to identify high-risk tumours is particularly important.
In the recently published study by Nizamani et al,
To assess improvement in vision, the authors compared preoperative vision and 1 month postoperative vision (see table 3 in original article) and concluded that vision improved with the treatment provided; however, this comparison does not support the conclusion since it is expected that vision will improve following cataract surgery. The diagnosis and subsequent treatment of Urrets-Zavalia syndrome was done after the surgery. To demonstrate the appropriateness of the management provided, comparison needs to be made between the first day and first...
We appreciate the comments by Drs Kahn and Rahman and agree that interpreting retrospective data must always be approached with caution.
Our study was devised to compare simultaneous combined phacoemulsification, PCIOL placement, pars plana vitrectomy and epiretinal membrane (ERM) peeling, with vitrectomy and membrane peeling alone.
The incidence of endophthalmitis following intravitreal anti-vascular endothelial growth factor (VEGF) injections has been reported to be 0–0.16%, but can result in severe and permanent loss of vision.
A retrospective review of medical records of patients diagnosed as endophthalmitis following intravitreal anti-VEGF injections administered between January 2007 and May 2012 at four tertiary eye-care centres in India were performed. Appropriate approval was obtained from the institutional review boards. The clinical, microbiological profile and management of all cases (O
A 91-year-old Caucasian woman presented at the New England Eye Center at Tufts Medical Center in Boston, Massachusetts in February 2012, with decreased vision in her left eye. She had a history of high blood pressure, thyroid disease and polymyalgia rheumatica. She was pseudophakic and had primary open angle glaucoma. On presentation, she was taking 2 mg of prednisone daily for polymyalgia rheumatica.
On ophthalmic examination, the best-corrected visual acuity (BCVA) was 20/25 in the right eye and 20/60 in the left eye. Dilated fundus examination showed mild retinal pigment epithelium (RPE) changes in the macula in her right eye and subretinal fluid involving the macula in her left eye (
No study to date has looked into the relationship between ocular biometrics with anisometropia exclusively; therefore, the purpose of this study was to determine the relationship between anisometropia and ocular biometrics.
In a cross-sectional study with multistage cluster sampling, 6311 people in the 40–64-year-old age group from the population of Shahroud, Iran, were selected. Of these, 5190 people participated in the study. For all participants, tests for visual acuity, cycloplegic and non-cycloplegic refraction, slit lamp test and fundoscopy were performed. All participants underwent biometric examinations using the Allegro Biograph (WaveLight AG, Erlangen, Germany).
Asymmetry of axial length, corneal power, vitreous chamber depth, anterior chamber depth, lens thickness and lens power were significantly more among participants who were anisometropic than those who were non-anisometropic. The correlation of anisometropia with axial length asymmetry was 0.735, 0.273 with corneal power, 0.183 with anterior chamber depth and 0.311 with lens power (p<0.001). In a multiple linear regression model, anisometropia was found to have significant associations with axial length asymmetry (standard coefficient (SC)=0.905), corneal power asymmetry (SC=0.350), lens power asymmetry (SC=0.454), nuclear opacity asymmetry (SC=0.074) and age (SC=0.28) (R2=85.1%). According to the linear regression model, corneal power had the strongest association with anisoastigmatism.
Axial length asymmetry has the strongest correlation with anisometropia; nonetheless, other components of ocular biometrics such as corneal power, lens opacity, lens power and anterior chamber depth are related to anisometropia as well. More than 10% of changes in anisometropia can be explained with changes in factors other than asymmetry of ocular biometrics and lens opacity.
To evaluate the refractive outcomes, prediction error (PE) and factors affecting PE in children with aphakia following congenital cataract surgery undergoing secondary intraocular lens (IOL) implantation.
We analysed the records of children less than 16 years old who underwent secondary IOL implantation for aphakia following congenital cataract surgery. PE and absolute PE for each case calculated 3 months following secondary IOL implantation were analysed. Multiple regression analysis was performed to determine the relationship between age at secondary IOL implantation, axial length, keratometry readings and PE.
174 eyes of 104 children were analysed. Mean age at surgery was 6.08±3.75 years. The mean PE was 1.65±2.46 dioptres (D) (range –3.25 to 7.5 D) and mean absolute PE was 2.15±1.68 D (range 0–7.5 D) at 3 months. There was a statistically significant difference in absolute PE between eyes in which IOL calculation was performed using IOL master (1.80±1.40 D) versus IOL calculation under general anaesthesia with contact method (2.43±1.83 D), p=0.01. Multiple regression analysis revealed an inverse relationship between age at secondary IOL implantation and mean absolute PE (p=0.01).
IOL power calculation with SRK II formula with sulcus placement of IOL gives favourable refractive outcomes. Though age-based refraction is targeted, a significant PE may be expected.
To compare capsular bag stability and posterior capsule opacification (PCO) of a plate-haptic intraocular lens (IOL) and a standard three-piece open-loop-haptic IOL of the same acrylic material.
In this randomised bilateral patient-masked and examiner-masked study, each patient received a microincision cataract surgery IOL (MICS IOL; Acri.Smart 46S=CT SHERIS 209M) in one eye and a small incision cataract surgery IOL (SICS IOL; AcriLyc 53N = CT 53N, both Carl Zeiss Meditec AG, Germany) as a control in the contralateral eye. Follow-up examinations were performed 1 h, 1 week, 1 month, 1 year and 3 years postoperatively. Anterior chamber depth (ACD) was measured and retroillumination images were performed at all postoperative follow-ups. Furthermore, uncorrected and corrected distance visual acuity, autorefraction and subjective refraction were assessed.
In total, 50 eyes of 25 patients were included. The ACD difference between the MICS IOL and the SICS IOL was not significant at any time point (p>0.05). Distance-corrected visual acuity at the 3-year follow-up was similar and not significantly different between the groups (p=0.48). Mean AQUA score in the MICS IOL group and in the SICS IOL group at the 3-year follow-up was 2.3 (SD ±2.3) and 2.1 (SD ±2.2), respectively (p=0.79).
The investigated hydrophilic acrylic plate-haptic MICS IOL with a hydrophobic surface showed comparable results concerning capsular bag stability and PCO rates up to 3 years compared with a SICS IOL of the same material.
Ocular surface squamous neoplasia (OSSN) is a spectrum of disease, on which few large series have been published, none in particular, from the UK. The purpose of this study is to describe experience of this condition from a UK national ocular oncology centre, including statistical analysis to elucidate factors significant in recurrence.
Retrospective review of case notes, clinical photographs and histopathology reports.
78 cases were included, of which 10 (12.8%) recurred during the follow-up time (mean 37 months). The 1-year recurrence rate was 10.9%, and 5-year recurrence rate was 18.5% using Kaplan-Meier analysis, with a mean time to recurrence of 9.5 months. Significant factors in recurrence were tumour size and first treatment given. Grade of OSSN, including presence of invasive disease and positive biopsy margins were not found to be statistically significant in recurrence.
OSSN in an uncommon disease in the UK population. However, when managed appropriately in a specialist centre, it is associated with good outcomes, even in recurrence situations.
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