Welcome to the Ophthalmology Journal News page! This page will showcase the latest news from the world of Ophthalmology, as published by The British Journal of Ophthalmology (BMJ).
For the British Ophthalmology Journal Archives, please visit http://bjo.bmj.com/ .
These news items are mainly specific study results that are relevant to the layman.
We have also added another news page with more ‘general’ Opthalmogy news here: Opthamologist News.
Furthermore, we have added a page with general news articles about Eye Health here: Eye Problems Articles , which is a good read for both patients and Ophthalmologists alike.
Ophthalmology Journal News:
We believe that some issues presented in the article by Kiire et al
Authors in the paragraph on cataract surgery pointed the increased risk of suprachoroidal haemorrhage in patients with high myopia, glaucoma, diabetes, atherosclerotic vascular disease or hypertension referencing to the interesting study,
We thank Grzybowski et al for their comments on our paper.
In our paper, we clearly acknowledge that the predominant technique for lens extraction is phacoemulsification, and that the risk of complications related to bleeding is rare. In one of the papers
We thank Chan et al
We read with interest on the article by Karabas et al
Karabas pointed out that their findings of choroidal thickness among the healthy control population were higher than other studies. Karabas reported subfoveal choroidal thickness of 349±70 µm and 151±31 µm in the nasal region.
Dacrocystorhinostomy—DCR (Gr. αo-o-o-oμα, Dakryon: Tear, Kystis: Bag, Rhis: nose, Stoma: mouth/opening) is a surgical creation of an opening between the lacrimal sac and nasal cavity, or a surgical procedure to restore the flow of tears into the nose from the lacrimal sac when the nasolacrimal duct does not function. If the procedure fails, the option is to then insert a conjunctivo-DCR tube (eg, Lester Jones tube) as a conduit between tear film and nasal passage (
Current literature identifies Celsus and Galen as some of the earliest physicians to attempt surgical correction of epiphora by applying hot cautery on the caruncle
Removal of the crystalline lens at the time of pars plana vitrectomy surgery is becoming an increasingly common surgical strategy in the management of vitreoretinal disease. Combined surgery provides enhanced peripheral retinal visualisation and the opportunity for a larger gaseous endotamponade and obviates the need for subsequent cataract surgery at a later date.
Numerous studies have explored the visual perceptions in phacoemulsification cataract surgery.
Fifty patients undergoing routine phacoemulsification cataract surgery were asked to complete a structured questionnaire immediately postoperatively. While all patients had been informed about the most serious risks relating to the surgery, there was great variability in the additional information provided. The patient perceptions of surgery were explored including parameters such as vision (brightness/colour of light and instrument/hand movement), sound (including buzzing/hissing of the...
We read an interesting ‘Clinical science’ article by Dotan et al
First, their prospective study was performed between May 2010 and November 2011. r-tPA was injected into patients who had undergone cataract surgery but whose condition had failed to respond to topical and subconjunctival steroid treatments. It was unclear why such a high number of patients required this treatment in a period as short as 18 months. We would like to know if they were faced with toxic anterior segment syndrome and if they investigated possible causes such as viscoelastics, irrigating solution, intraocular lens material etc.
Second, they prepared r-tPA by distributing insulin injectors stored at –80°C. Whenever necessary they used r-tPA by defrosting the same insulin injectors at 24°C. Some injections...
Adaptive optics scanning light ophthalmoscopy (AOSLO) enables direct visualisation of the cone mosaic, with metrics such as cone density and cell spacing used to assess the integrity or health of the mosaic. Here we examined the interobserver and inter-instrument reliability of cone density measurements.
For the interobserver reliability study, 30 subjects with no vision-limiting pathology were imaged. Three image sequences were acquired at a single parafoveal location and aligned to ensure that the three images were from the same retinal location. Ten observers used a semiautomated algorithm to identify the cones in each image, and this was repeated three times for each image. To assess inter-instrument reliability, 20 subjects were imaged at eight parafoveal locations on one AOSLO, followed by the same set of locations on the second AOSLO. A single observer manually aligned the pairs of images and used the semiautomated algorithm to identify the cones in each image.
Based on a factorial study design model and a variance components model, the interobserver study's largest contribution to variability was the subject (95.72%) while the observer's contribution was only 1.03%. For the inter-instrument study, an average cone density intraclass correlation coefficient (ICC) of between 0.931 and 0.975 was calculated.
With the AOSLOs used here, reliable cone density measurements can be obtained between observers and between instruments. Additional work is needed to determine how these results vary with differences in image quality.
To describe a novel submerged hydro-separation (SubHyS) technique followed by anterior corneal dissection to prepare a Descemet endothelial graft (DEG) for Descemet's membrane endothelial keratoplasty from human donor corneas.
30 human donor corneas were immersed in liquid (organ culture (OC) storage medium). Using a 25-gauge needle, approximately 0.3 mL of OC was injected (SubHyS) in the posterior stroma to create a liquid bubble. The bubbled cornea was mounted onto a modified artificial chamber with the epithelial side facing the air. The endothelium was protected with a viscoelastic solution. The anterior cornea was excised with a Barron radial vacuum trephine and the residual peripheral stroma was removed manually using micro-scissors. The DEG was dismounted and washed. The endothelial cell density (ECD) and mortality of the prepared DEG was determined. All the DEGs were preserved in deturgescent medium for 7 days using a cornea claw which was fixed to the sclera. ECD and mortality were checked post preservation.
Complete detachment of Descemet's membrane and stroma was achieved in all 30 cases. Bubble burst was observed in five cases (excluded from the study) due to overfilling of the liquid. The average diameter of the excised DEG was 10.96 mm. The average endothelial cell loss post preservation was 27.69%. Histological analysis confirmed elimination of the residual stroma (n=13).
The DEGs can be preserved in a deturgescent medium for up to 7 days. The procedure provides a standardised, pre-validated (quality assured), pre-separated, no-touch, ready-to-use tissue and also reduces the preparation time. Further, the tissues can be trephined as per the surgeon’s convenience and can either be rolled or a contact lens could be used for final delivery of the DEG using a surgical glide.
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