Opthamologist News

Welcome to the Opthamologist News page (Ophthalmologist News ).

This page is intended as a quick update on whats going on in the world of Opthamology, including ophthalmology studies, news and general articles. Have a browse and see if something catches your eye.

We have also added another  Opthalmology news page, that includes only the latest medical studies and results, so if you are an Opthamologist, then it is also worth a read: Ophthalmology Journal.

For our ‘General Eye Health’ news page, please see: Eye Health.

Enjoy reading.

Opthamologist News:

Authors: Szumny D, Sozański T, Kucharska AZ, Dziewiszek W, Piórecki N, Magdalan J, Chlebda-Sieragowska E, Kupczynski R, Szeląg A, Szumny A Abstract One of the most common diseases of old age in modern societies is glaucoma. It is strongly connected with increased intraocular pressure (IOP) and could permanently damage vision in the affected eye. As there are only a limited number of chemical compounds that can decrease IOP as well as blood flow in eye vessels, the up-to-date investigation of new molecules is important. The chemical composition of the dried Cornelian cherry (Cornus mas L.) polar, iridoid-polyphenol-rich fraction was investigated. Loganic acid (50%) and pelargonidin-3-galactoside (7%) were found as the main components. Among the other constituents, iridoid compoun...

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Posted: July 3, 2015, 11:40 pm
In The Lancet, Miles Kiernan and colleagues1 report an unusual case of a patient who developed sight-threatening ophthalmic problems after upper arm surgery. The ipsilateral symptoms and signs in this case (red eye, proptosis, limited eye movements, raised intraocular pressure, and retinal haemorrhages) are all classic presenting features of orbital venous hypertension. The most common cause is an arteriovenous fistula in the cavernous sinus and ophthalmologists are well aware of the need to investigate this possibility in any patient presenting with a unilateral red eye and raised intraocular pressure. (Source: LANCET)
Posted: July 3, 2015, 10:32 pm
Abstract In recent years, IgG4-related ophthalmic disease (IgG4-ROD) has emerged as a common cause of orbital inflammation, accounting for a substantial proportion of idiopathic orbital inflammation and lymphoid hyperplasia. The last pooled analysis of published cases was conducted in 2012, but a large number of new cases have been added to the literature since then. In this review, we present the demographic, clinical, histological, and treatment data for 172 published cases of biopsy-confirmed IgG4-ROD. Results are accompanied by a review of the relevant literature. (Source: Current Allergy and Asthma Reports)
Posted: July 3, 2015, 5:27 pm
Conclusions: The long-term neurodevelopmental outcome in children treated with IVIg was not different from that in children treated with placebo. Standardized long-term follow-up studies with large enough case series and sufficient power are needed to replicate these findings.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Posted: July 3, 2015, 12:15 pm
Photochem. Photobiol. Sci., 2015, Advance ArticleDOI: 10.1039/C5PP00171D, PerspectiveP. R. O'Neill, N. GautamThis perspective highlights recent advances in the design of optogenetic tools that provide dynamic subcellular control over signaling and cell behaviour.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Photochem. Photobiol. Sci. latest articles)
Posted: July 3, 2015, 9:59 am
Authors: De Sousa SM, Earls P, McCormack AI Abstract UNLABELLED: Pituitary hyperplasia (PH) occurs in heterogeneous settings and remains under-recognised. Increased awareness of this condition and its natural history should circumvent unnecessary trans-sphenoidal surgery. We performed an observational case series of patients referred to a single endocrinologist over a 3-year period. Four young women were identified with PH manifesting as diffuse, symmetrical pituitary enlargement near or touching the optic apparatus on MRI. The first woman presented with primary hypothyroidism and likely had thyrotroph hyperplasia given prompt resolution with thyroxine. The second and third women were diagnosed with pathological gonadotroph hyperplasia due to primary gonadal insufficiency, with his...

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Posted: July 3, 2015, 8:04 am
Eye advance online publication, July 3 2015. doi:10.1038/eye.2015.116 Author: O A Mahroo (Source: Eye)
Posted: July 3, 2015, 6:00 am
Trabeculectomy ab interno (trabectome): yet another possibility in the treatment of uncontrolled glaucomatocyclitic crisis under systemic valganciclovir therapy? Eye advance online publication, July 3 2015. doi:10.1038/eye.2015.112 Authors: M Pahlitzsch, N Torun, J Gonnermann, A-K B Maier, U Pleyer, E Bertelmann, A Joussen & M K J Klamann (Source: Eye)
Posted: July 3, 2015, 6:00 am
Authors: P S Kemp & T A Oetting (Source: Eye)
Posted: July 3, 2015, 6:00 am
Authors: M Gharbiya, R Malagola, C Mariotti, F Parisi, U De Vico, C Ganino & F Grandinetti (Source: Eye)
Posted: July 3, 2015, 6:00 am
Authors: I H Yusuf, R Smith & C K Patel (Source: Eye)

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Posted: July 3, 2015, 6:00 am
Eye advance online publication, July 3 2015. doi:10.1038/eye.2015.119 Author: J Lochhead (Source: Eye)
Posted: July 3, 2015, 6:00 am
(Source: Clinical and Experimental Ophthalmology)
Posted: July 2, 2015, 11:00 pm
To evaluate 6-year results of standardized epithelium-off corneal collagen cross-linking (CXL) for treatment of progressive corneal ectasia. (Source: American Journal of Ophthalmology)
Posted: July 2, 2015, 11:00 pm
Publication date: Available online 2 July 2015 Source:Progress in Retinal and Eye Research Author(s): Keith M. Meek , Carlo Knupp The corneal stroma plays several pivotal roles within the eye. Optically, it is the main refracting lens and thus has to combine almost perfect transmission of visible light with precise shape, in order to focus incoming light. Furthermore, mechanically it has to be extremely tough to protect the inner contents of the eye. These functions are governed by its structure at all hierarchical levels. The basic principles of corneal structure and transparency have been known for some time, but in recent years x-ray scattering and other methods have revealed that the details of this structure are far more complex than previously thought and that the intricacy of the ...
Posted: July 2, 2015, 11:00 pm
Abstract P values associated with null hypothesis significance testing (NHST) are almost universal in the ophthalmic literature. A p value < 0.05 is traditionally considered as ‘significant’. This concept may deflect further thought about the veracity of the results. P values influence the publishability of the data, and have flow‐on effects for funding success and the direction of future research. Despite their importance, the problems inherent in p values have been recognized since their inception, and in more recent years have been increasingly highlighted in some scientific fields. In this review, we aim to bring the problems associated with p values and NHST to the attention of the ophthalmic research community. We do not offer a universal solution to the problem of determini...
Posted: July 2, 2015, 11:00 pm
Publication date: 1 July 2015 Source:Neuron, Volume 87, Issue 1 Author(s): Han Kyoung Choe , Michael Douglas Reed , Nora Benavidez , Daniel Montgomery , Natalie Soares , Yeong Shin Yim , Gloria B. Choi Meaningful social interactions modify behavioral responses to sensory stimuli. The neural mechanisms underlying the entrainment of neutral sensory stimuli to salient social cues to produce social learning remain unknown. We used odor-driven behavioral paradigms to ask if oxytocin, a neuropeptide implicated in various social behaviors, plays a crucial role in the formation of learned associations between odor and socially significant cues. Through genetic, optogenetic, and pharmacological manipulations, we show that oxytocin receptor signaling is crucial for entrainment of odor to socia...
Posted: July 2, 2015, 11:00 pm
To evaluate ranibizumab 0.5 mg using bimonthly monitoring and individualized re-treatment after monthly follow-up for 6 months in patients with visual impairment due to diabetic macular edema (DME). (Source: Ophthalmology)
Posted: July 2, 2015, 11:00 pm
Publication date: Available online 2 July 2015 Source:Materials Science and Engineering: B Author(s): T. Dimopoulos , M. Bauch , R.A. Wibowo , N. Bansal , R. Hamid , M. Auer , M. Jäger , E.J.W. List-Kratochvil We investigate the structural, electrical and optical properties of transparent electrodes, consisting of Al-doped ZnO (AZO) and ultrathin Au layers, sputtered on polyethylene terephthalate (PET). These electrodes are relevant for optoelectronic devices and thin film photovoltaics. When deposited on AZO, Au films as thin as 3nm form electrically conductive, meandering structures, whereas uniform Au films are obtained from a thickness of 5nm. The sheet resistance decreases with Au thickness, reaching 7Ω for 11nm-thick Au. AZO/Au/AZO trilayers combine lowest resistance with highest...

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Posted: July 2, 2015, 11:00 pm
ConclusionGS patients may be differentiated from those with SG or PG by their IOP response and SG may be differentiated from PG patients by their change in OCV following an ibopamine challenge. (Source: Clinical and Experimental Ophthalmology)
Posted: July 2, 2015, 11:00 pm

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